Imaging in living cells using νB-H Raman spectroscopy: monitoring COSAN uptake.

Raman microspectroscopy for non-invasive biochemical analysis of single cells.

Recent developments in biomedical vibrational spectroscopy now permit the non-invasive imaging of cells and tissues within both the laboratory and clinical settings. The rapid nature and diagnostic potential of both Raman and FTIR (Fourier-transform IR) spectroscopy have resulted in their widespread application to a number of biological fields including fundamental cell biology, medical imaging...

Investigation in to Properties of Polyurethane Closed Cell by High Loading of SiO2 Nanoparticles

In this research the composition of polyurethane closed cell (PUCC) with two different concentrations of SiO2 nanoparticles (1.0 and 2.0 wt%) have been prepared. Optical microscopy and SEM imaging, watering uptake, FTIR and Raman spectroscopy of the synthesized samples were carried out. The optical microscopy imaging of samples showed differences in the appearance of matrix produ...

Label-free microscopic bioimaging by means of confocal Raman spectroscopy on living glioblastoma cells

Investigating Effects of Proteasome Inhibitor on Multiple Myeloma Cells Using Confocal Raman Microscopy

Due to its label-free and non-destructive nature, applications of Raman spectroscopic imaging in monitoring therapeutic responses at the cellular level are growing. We have recently developed a high-speed confocal Raman microscopy system to image living biological specimens with high spatial resolution and sensitivity. In the present study, we have applied this system to monitor the effects of ...

Fluorescence and SERS Imaging for the Simultaneous Absolute Quantification of Multiple miRNAs in Living Cells.

The simultaneous imaging and quantification of multiple intracellular microRNAs (miRNAs) are particularly desirable for the early diagnosis of cancers. However, simultaneous direct imaging with absolute quantification of multiple intracellular RNAs remains a great challenge, particularly for miRNAs, which have significantly different expression levels in living cells. We designed dual-signal sw...